Orange County Mental Health Treatment Center
D’AMORE AND KETAMINE THERAPY
In order to stay at the vanguard of mental wellness recovery, D’Amore Healthcare now implements ketamine treatment as one of our pharmacotherapy tracks. In recent studies, there has been an increasing amount of compelling evidence that low doses of ketamine can bring about dramatic and lasting improvement in a number of mental health conditions. When administered as a supplement to one of our personalized treatment plans, ketamine therapy can put you in the position to bring balance and autonomy back to your life.
PARTNERING WITH D’AMORE HEALTHCARE
The expert staff at D’Amore Healthcare takes your entire medical and psychological history into consideration. We then create a customized treatment plan tailored to your needs as a patient, with modalities ranging from individual and group sessions to our signature “Build Me Up” program.
Much like our safe and comfortable mental health treatment facility, a properly administered and supervised course of ketamine therapy when appropriate can increase the efficacy of these strategies. This track can be an effective alternative for the treatment of chronic conditions that have been resistant to conventional approaches.
WHAT IS KETAMINE?
Ketamine is a medication first approved for use in 1970 and has since been used primarily as an anesthetic. Studies conducted in the 2000s, however, showed ketamine to be an effective and rapidly-acting anti-depressant when administered in sub-anesthetic doses. If our clinicians believe that ketamine would be effective for you, you could begin to notice an improved mood within 4 to 24 hours after infusion therapy.
WHAT IS ESKETAMINE?
Esketamine is a pharmaceutical drug derived from ketamine. It is typically sold under the brand names Ketanest and Spravato. Similar to ketamine, esketamine acts as an anesthetic and a dissociative that is used to treat Treatment-Resistant Depression (TRD). In February of 2019, the FDA approved esketamine in the form of a nasal spray for the effective treatment of Major Depressive Disorder for people who have not been successful with traditional antidepressant treatments.
ESKETAMINE FOR TREATMENT RESISTANT DEPRESSION (TRD)
Treatment-Resistant Depression affects more than 2 million people in the US alone. A patient is diagnosed with TRD after they attempt to treat their Major Depressive Disorder with at least 2 different antidepressant medications without a noticeable improvement in their symptoms. Esketamine is able to ‘jump start’ the treatment of depression by serving as an NMDA-antagonist, this works to increase the brain’s ability to respond to antidepressant medication. Esketamine is used in conjunction with an oral antidepressant medication, together they are able to minimize the symptoms of depression in people who haven’t found relief from antidepressants in the past.
HOW DOES ESKETAMINE TREATMENT WORK?
Esketamine can be taken as a nasal spray under the brand name Spravato. Each nasal spray device contains 28 mg of Esketamine. Most patients prefer the easy and non-invasive nasal spray over the intravenous IV infusions that are typically used in ketamine therapy. Patients will generally begin treatment by self-administering one spray to each of their nostrils while under the supervision of a medical professional. This dosage will typically be administered twice a week for a 4 week period. For longterm treatments, patients have often moved up to 3 sprays, once a week in order to maintain the positive effects. Patients have been reported to experience a significant reduction of the symptoms of their depression in the 5 to 7 week period after beginning their treatment.